Σταδιοποίηση σε Ca Νεφρού
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Ca Νεφρού |
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AJCC Stages |
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Stages |
T |
N |
M |
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I |
T1 |
N0 |
M0 |
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II |
T2 |
N0 |
M0 |
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III |
T1 or T2 |
N1 |
M0 |
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T3 |
N0 or N1 |
M0 |
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IV |
T4 |
Any N |
M0 |
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Any T |
Any N |
M1 |
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Σύγκριση Robson and TNM Staging |
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Robson |
Definitions |
TNM |
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I |
Tumor ≤ 2.5 cm and confined to kidney |
T1 |
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Tumor > 2.5 cm and confined to kidney |
T1-T2 |
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II |
Tumor extends into perinephric fat or adrenal |
T3a if involves perinephric fat, T4 if involves ipsilateral adrenal |
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IIIA |
Tumor invades renal vein |
T3a |
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Tumor extends into inferior vena cava |
T3b below the diaphragm |
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IIIB |
Lymph node involvement |
N0-N1, M0 |
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IIIC |
Involvement of local vasculature and lymph nodes |
T3a-c, N0-N1 |
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IVA |
Involvement of adjacent organs (except ipsilateral adrenal) |
T4 |
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IVB |
Distant metastases |
M1 |
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(T) Primary Tumor |
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TX |
Primary tumor cannot be assessed |
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T0 |
No evidence of primary tumor |
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T1 |
Tumor ≤ 7 cm in greatest dimension, limited to the kidney |
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T1a |
Tumor ≤ 4 cm in greatest dimension, limited to the kidney |
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T1b |
Tumor > 4 cm but ≤ 7 cm in greatest dimension, limited to the kidney |
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T2 |
Tumor > 7 cm in greatest dimension, limited to the kidney |
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T2a |
Tumor > 7 cm but ≤ 10 cm in greatest dimension, limited to the kidney |
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T2b |
Tumor > 10 cm, limited to the kidney |
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T3 |
Tumor extends into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond Gerota fascia |
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T3a |
Tumor grossly extends into the renal vein or its segmental (muscle containing) branches, or tumor invades perirenal &/or renal sinus fat but not beyond Gerota fascia |
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T3b |
Tumor grossly extends into the vena cava below the diaphragm |
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T3c |
Tumor grossly extends into the vena cava above the diaphragm or invades the wall of the vena cava |
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T4 |
Tumor invades beyond Gerota fascia (including contiguous extension into the ipsilateral adrenal gland) |
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(N) Regional Lymph Nodes |
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NX |
Regional lymph nodes were not assessed |
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N0 |
No regional lymph node metastasis |
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N1 |
Metastasis in regional lymph node(s) |
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(M) Distant Metastasis |
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M0 |
No distant metastasis |
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M1 |
Distant metastasis |
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Χαρακτηριστικά Επέκτασης |
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Hematogenous, lymphatic, &/or direct invasion
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25-40% present with metastatic disease
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Κατηγοριοποίηση (Ιστολογικοί Τύποι) |
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4 major histopathologic subtypes of renal cell Ca
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